Ya it really has to do with a number of factors on how long you can leave a tank unsupervised, however, in general the smaller you go, the more work they become and the less time you can be away from regular maintenance.
This is for a number of factors, also. Mainly due to the volume of water you're working with......also the fact that nano tank support (i.e. hardware manufatured in mass) is a fraction of output by the industry.
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It's not the big things which lead to failure in this hobby, it's the small things
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