[Glimmerman911]

This doesn't answer your question, but what benefit do you hope to get from using 1 manifold instead of having the manifold + closed loop?

Is this in a fish room where you don't care what everything looks like, or is it in a living room so you have to have everything under your stand?

One option would be to use something like a barracuda pump on a 1" manifold, with 6-8 t's, going to 1/2" loc lines. That will give you approx. 2500gph depending on the total head. That would cover your tank flow. This is what I have setup as a closed loop, it works very well.

The refugium flow, depending on whether you have a sump or not as well, would be fed seperately, possibly from a drain line depending on the height of your fuge. Then use a single pump for your chaeto rolling. Depending on the dimensions of the chaeto ball area in the fuge, you could use the smallest tunze stream, or go with something smaller such as a quiet-one, or eheim, or mag pump. This setup would have two pumps.

Need more information about your setup, heights of various tanks, etc. to give you more options.